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Polyphenols are the essential organic compounds for human health. They biosynthesized in plants. They have a very potent antioxidant characters therefore, they are the main protector of human life against oxidative stress which leads to about 90% of hard diseases such as cancers, cardiovascular problems, diabetes, neuroproblems, and many others. Thus now, polyphenols become the top demanded natural compounds to be used largely in folk medicine every where in the world. Also, new pharmaceutical compounds came up and demanded everywhere in the world. The recent researches confirmed that these compounds are the best and strongest fighter against oxidative stress and keep the human healthy with no any stress or health trouble.