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The mechanisms of neurodegenerative diseases are elucidated in this book. It throws light on the pathophysiological complexities of the mechanisms and factors that are most probably involved in a number of neurodegenerative and neuroinflammatory diseases including Parkinson disease, Alzheimer's disease, and other Dementia. The spectrum of various factors concerned with neurodegeneration, like oxidative stress, regulators, zinc, astrocytes, protein aggregation, caspases and secretase, cholesterol, oligodendrocytes, microglia, etc., have been elucidated in the light of disease progression. In addition, to disease mechanism, new approaches to therapeutic interventions have also been described. This book will serve as a valuable source of information for students, clinicians, scientists, etc.