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Autism spectrum disorder (ASD) is a developmental disorder characterised by disturbance in language, perception and social skills that affects an estimated 1 2 per 1,000 people worldwide (although the number is as high as 20 per 1000 in the US). In 2013, a single category of ASD united several related conditions (classical autism, Asperger s syndrome, Fragile X Syndrome, Landau-Kleffner Syndrome, Rett syndrome, childhood disintegrative disorder, and PDD-NOS) was included in the DSM-5, with the aim to provide a more precise definition to will guide more consistent diagnoses and treatment. While studies have suggested a disturbance in neural metabolism in patients with ADS, the exact cause of the condition still remains unknown.§Managing Autism Spectrum Disorder will serve a practical handbook supporting the diagnosis, treatment and long-term management of this condition, including behavioral therapies and emerging treatments.