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The Ocean, which is called the 'Mother of origin of life', is also the source of structurally unique natural products that are mainly accumulated in living organisms. Several of these compounds how pharmacological activities and are helpful for the invention and discovery of bioactive Compound, primarily for deadly diseases like cancer, acquire immuno-deficiency syndrome, etc. The lives saving drugs are mainly found abundantly in microorganisms, algae and invertebrates and vertebrates. Modern technologies have opened vast areas of research for the extraction of biomedical compounds from ocean and seas to treat the deadly diseases. Acanthus ilicifolius (family of Acanthaceae) is a valuable medicinal plant that is widespread in tropical Asia and Africa, through Malaya to Polynesia. Acanthus ilicifolius extracts have been used in various folk medicines as remedies against rheumatism, neuralgia, poison arrow wounds, coughs, asthma and bacterial infections with subsequent scientific supports to these.